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Pikamilon and it's Place in the Group of
Well-Known Nootropic Drugs
[Article in Russian]
Institute of Pharmacology,
8, Baltiyskaya St., Moscow, 125315, USSR
Abstract
Pikamilon - N-nicotinoyl-GABA is a new vasoactive drug with nootropic
properties. It has anti-amnesic activity on two models of amnesia of passive
avoidance response, caused by maximum electro shock and scopolamine on mice.
Pikamilon increases exploratory behavior in open field. In comparison with the known nootropic drugs,
pikamilon produces a specific antiamnestic effecy in lower doses, than piracetam, etiracetam, aniracetam.
Effects of deanol, aceglumat, centrophenoxine, and
pikamilon, received in the same doses, are similar. But
pikamilon is less potent than nicergoline.
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